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PhD fellowship in functional cardiac genomics

We are offering a PhD fellowship in functional cardiac genomics commencing on the 1 December 2024 or as soon as possible hereafter.



Our group and research
The newly started group of Functional Genomics is headed by assistant professor Pia Rengtved Lundegaard. We have a keen interest in the structure and function of the atrium, and to study this we use the zebrafish as a model organism. We study all aspects of the development, morphogenesis and function of the heart, with a particular interest in the atrium, and how mutations in genes associated with human cardiac disorders lead to cardiac dysfunction (Ahlberg et al. Nature Comms. 2018, Collins et al, PNAS 2019, Vad et al, JACC: Basic to Transnational Science, 2023).
Lundegaard group website



Project description

We are looking for a dedicated Ph.D student, who has a keen interest in understanding the role of genes involved in atrial form and function. The PhD student recruited for this project will work on existing zebrafish mutants available in the lab, as well as generate additional mutant and transgenic zebrafish models. Techniques include CRISPR-Cas9 genome editing, RNA sequencing (bulk and single cell), molecular biology methods, protein analysis and high-resolution imaging using confocal microscopy.
An interest or previous experience in R-studio or Python is an advantage as well.



Principal supervisor is Associate professor Cathrine Ørskov.

Project supervisor: Assistant professor Pia Rengtved Lundegaard, plundegaard@sund.ku.dk. All information regarding the advertisement should be directed to assistant professor Pia Rengtved Lundegaard.

Start: Date

Duration: 3 years as a PhD student



Job description
Your key tasks as a PhD fellow at SUND are:

  • Carrying through an independent research project under supervision.
  • Completing PhD courses or other equivalent education corresponding to approximately 30 ECTS points.
  • Participating in active research environments including a stay at another research team.
  • Obtaining experience with teaching or other types of dissemination related to your PhD project
  • Teaching and disseminating your knowledge.
  • Writing a PhD thesis on the grounds of your project


Key criteria for the assessment of applicants
Applicants must have qualifications corresponding to a master’s degree related to the subject area of the project, e.g. molecular biology, cell biology, developmental biology, immunology or biophysics. Please note that your master’s degree must be equivalent to a Danish master’s degree (two years). Experience in working with the zebrafish model is required for this post.

Other important criteria are:

  • The grade point average achieved
  • Professional qualifications relevant to the PhD project
  • Previous publications
  • Relevant work experience
  • Other professional activities
  • A curious mind-set with a strong interest in cardiac biology
  • Language skills


Place of employment

The place of employment is at the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories at the Maersk Building, and a large shared zebrafish facility.



Terms of employment
The average weekly working hours are 37 hours per week.

The position is a fixed-term position limited to a period of 3 years. The start date is December 1st 2024 or as soon thereafter.

The employment is conditioned upon the applicant’s success­ful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.

The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree.



Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary starts at approximately 30,700 DKK/Roughly 4,100 EUR (April 2024 level) plus pension.



Questions
For specific information about the PhD fellowship, please contact the principal supervisor.

General information about PhD studies at the Faculty of Health and Medical Sciences is available at the Graduate School’s website: https://healthsciences.ku.dk/phd/guidelines/



Application procedure
Your application must be submitted electronically by clicking ‘Apply now’ below. The application must include the following documents in PDF format:

1. Motivated letter of application (max. one page)

2. CV incl. education, experience, language skills and other skills relevant for the position

3. Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted. As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database/?set_language=en. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science

4. Publication list (if possible)



Application deadline: 30 September 2024, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.



The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.



Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.



You find information about the recruitment process at: http://employment.ku.dk/faculty/recruitment-process/



The applicants will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.



Interviews are expected to be held in week 43.

The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.



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